Publications

 

Research after Arriving at Ohio University (2007-Present)

37. Hao Chen and R. Graham Cooks, “Historical Perspectives in the Study of Ion Chemistry by Mass Spectrometry: From the Gas Phase to Solution”, in MS Investigations of Reactive Intermediates in Solution, Leonardo S. Santos Ed., Wiley-VCH, Submitted (Invited).

36. Livia S. Eberlin, Yu Xia, Hao Chen and R. Graham Cooks, "Atmospheric Pressure Thermal Dissociation of Phospho- and Sulfopeptides", J. Am. Soc. Mass Spectrom., 2008, In press.

35. Zhixin Miao and Hao Chen, "Direct Analysis of Liquid Samples by Desorption Electrospray Ionization-Mass Spectrometry (DESI-MS)", J. Am. Soc. Mass Spectrom., 2008, In press.

34. Wen-Ping Peng, Mike Goodwin, Hao Chen, R. Graham Cooks, Jonathan Wilker, "Thermal Formation of Mixed-Metal Inorganic Complexes at Atmospheric Pressure", 2008, Submitted.

33. Hao Chen, Livia S. Eberlin, Marcela Nefliu, Rodinei Augusti and R. Graham Cooks, "Organic Reactions of Ionic Intermediates Promoted by Atmospheric Pressure Thermal Activation", Angew. Chem. Int. Ed., 2008, 47, 3422-3425.

32. Ismael Cotte-Rodriguez, Heriberto Hernández-Soto, Hao Chen, R. Graham Cooks "In-situ Trace Detection of Peroxide Explosives by Complexation During Desorption Electrospray Ionization and Desorption Atmospheric Pressure Chemical Ionization", Anal. Chem., 2008, 80, 1512-1519.

 

Previous Research

31. Guangming Huang, Hao Chen, Xinrong Zhang, R. Graham Cooks and Zheng Ouyang, “Rapid Screening of Anabolic Steroids in Urine by Reactive Desorption Electrospray Ionization”, Anal. Chem., 2007, 79, 8327 - 8332.

30. Hao Chen, Livia S. Eberlin, R. Graham Cooks, "Neutral Fragment Mass Spectra via Ambient Thermal Dissociation of Peptide/Protein Ions", J. Am. Chem. Soc., 2007, 129, 5880-5886.

† Reported by J. Proteome Res.

29. Hao Chen, Zheng Ouyang, R. Graham Cooks, "Thermal Production and Reactions of Organic Ions at Atmospheric Pressure", Angew. Chem. Int. Ed., 2006, 3656-3660.

† Featured as a Very Important Paper (VIP).

28. R. Graham Cooks, Hao Chen, Marcos N. Eberlin, Xubin Zheng and W. Andy Tao, “Polar Acetalization and Transacetalization in the Gas Phase: The Eberlin Reaction”, Chem. Rev. 2006, 106, 188-211.

27. Hao Chen, Ismael Cotte-Rodriguez and R. Graham Cooks, “cis-Diol Functional Group Recognition by Reactive Desorption Electrospray Ionization”, Chem. Commun. 2006, 597-599.

† Featured as a Hot Article & Front Cover.

26. Ismael Cotte-Rodriguez, Hao Chen and R. Graham Cooks, “Rapid Trace Detection of Triacetone Triperoxide (TATP) by Complexation Reactions during Desorption Electrospray Ionization”, Chem. Commun. 2006, 953-955.

† Reported by Chemical & Engineering News and Chemical Sciences.

† Featured as a Hot Article & Front Cover.

† Highlighted as one of Top 10 Articles in 2006 February Issue.

25. Rodinei Augusti, Hao Chen, Livia Schiavinato Eberlin, Marcela Nefliub and R. Graham Cooks, “Atmospheric pressure Eberlin transacetalization reactions in the heterogeneous liquid/gas phase”, Int. J. Mass Spectrom., 2006, 253, 281-287.

24. Daniel J. Goebbert, Hao Chen and Paul G. Wenthold, “Collision-Induced Dissociation Studies of Protonated Ether–(H2O)n (n=1–3) Clusters”, J. Mass Spectrom. 2006, 41, 242–247.

23. Hao Chen, Dina R. Justes and R. Graham Cooks, “Proton Affinities of N-Heterocyclic Carbene Super Bases”, Org. Lett. 2005, 7, 3949-3952

22. Hao Chen, R. Graham Cooks, Eduardo C. Meurer and Marcos N. Eberlin, “Hydrogen/Chlorine Exchange Reactions of Gaseous Carbanions”, J. Am. Soc. Mass Spectrom. 2005, 2045-2051.

21. Igor A. Popov, Hao Chen, Oleg N. Kharybin, Eugene N. Nikolaev and R. Graham Cooks, “Detection of Explosives on Solid Surfaces by Thermal Desorption and Ambient Ion/Molecule Reactions”, Chem. Commun., 2005, 1953-1955

20. Yishu Song, Hao Chen and R. Graham Cooks, “Reactivity of Acetonyl Anion with Nitroaromatics: An Atmospheric Pressure Chemical Ionization Study”, Rapid Commun. Mass Spectrom. 2005, 19, 3493-3499.

19. Huanwen Chen, Ruifeng Xu, Hao Chen, R. Graham Cooks and Zheng Ouyang, "Ion/Molecule Reactions in a Miniature RIT Mass Spectrometer", J. Mass Spectrom., 2005, 40, 1403-1411.

18. Hao Chen, Xubin Zheng, Pengxiang Yang and R. Graham Cooks, “Reduction of Nitroaromatics to Arylnitrenium Ions by Vinyl Halide Cations” Chem. Commun., 2004, 688-689.

17. Hao Chen, Huanwen Chen and R. Graham Cooks, “Generation of Arylnitrenium Ions by Nitro-reduction and Gas-Phase Synthesis of N-Heterocycles” J. Am. Soc. Mass Spectrom., 2004, 15, 1675-1688.

16. Hao Chen, Huanwen Chen and R. Graham Cooks, "Meisenheimer Complexes Bonded at Carbon and at Oxygen in the Gas Phase", J. Am. Soc. Mass Spectrom., 2004, 15, 998-1004.

15. Eduardo C. Meurer, Hao Chen, Leah Riter, Ismael Cotte-Rodriguez, Marcos N. Eberlin and R. Graham Cooks, “Gas-Phase Reactions for Selective Detection of the Explosives TNT and RDX” Chem. Commun., 2004, 40-41.

14. Eduardo C. Meurer, Hao Chen, Leah S. Riter, Marcos N. Eberlin and R. Graham Cooks, "Meerwein Reaction of Phosphonium Ions with Epoxides and Thioepoxides in the Gas Phase," J. Am. Soc. Mass Spectrom., 2004, 15, 398-405.

13. Rodinei Augusti, Daniella V. Augusti, Hao Chen, and R. Graham Cooks, “Gas-Phase Halide Affinity of Aliphatic Alcohols Estimated by the Kinetic Method” Eur. J. Mass Spectrom., 2004, 10, 847.

12. Rodinei Augusti, Maciej Turowski, Hao Chen and R. Graham Cooks, " Dissociation of Ionized Benzophenones Investigated by the Kinetic Method: Effective Temperature, Steric Effects, and Gas-Phase CO+• Affinities of Phenyl Radicals” J. Mass Spectrom., 2004, 39, 558-564.

11. Habib Bagheri, Hao Chen and R. Graham Cooks, “Chiral Recognition by Proton Transfer Reactions with Optically Active Amines and Alcohols” Chem. Commun., 2004, 2740-2741.

10. Hao Chen, Xubin Zheng and R. Graham Cooks, “Ketalization of Phosphonium Ions by 1, 4-Dioxane: Selective Detection of the Chemical Warfare Agent Simulant DMMP in Mixtures Using Ion/Molecule Reactions” J. Am. Soc. Mass Spectrom., 2003, 14, 182–188.

9. Leah S. Riter, Eduardo C. Meurer, Eric S. Handberg, Brian C. Laughlin, Hao Chen, Garth E. Patterson and R. Graham Cooks, “Ion /Molecule Reactions Performed in a Miniature Cylindrical Ion Trap Mass Spectrometer”, Analyst, 2003, 28, 1112-1118.

† Featured as a Front Cover.

8. Hao Chen and Yuegang Zuo, “Identification of Flavonol Glycosides in American Cranberry Fruit”, Food Chem. 2007, 101, 1357.

7. Yiwei Deng, Kai Zhang, Hao Chen, Taixing Wu, Metthew Krzyaniak, Amina Wellons, Dawn Bolla, Kenneth Douglas, Yuegang Zuo, "Iron-catalyzed photochemical transformation of benzoic acid in atmospheric liquids: Product identification and reaction mechanisms", Atmos. Environ., 2006,      40, 3665-3676

6. Yuegang Zuo and Hao Chen, ”Determination of Sulfite, Sulfate and Hydroxymethanesulfonate in Atmospheric Water by Ion-Pair HPLC Technique” Talanta, 2003, 59, 875-881.

5. Yuegang Zuo, Hao Chen and Yiwei Deng, “Simultaneous Determination of Catechins, Phenolic Acids and Caffeine in Green, Oolong, Black and Pu-erh Teas Using HPLC with a Photodiode Array Detector” Talanta, 2002, 57, 307-316.

4. Hao Chen, Yuegang Zuo, and Yiwei Deng, “Separation and Determination of Flavonoids and Other Phenolic Compounds in Cranberry Juice by HPLC” J. Chromator., A, 2001, 913, 387-395.

 3. Yonggang Yang, Hao Chen, Geng Tang and Jianxun Wen, “Synthesis and Mesomorphic Properties of Some Fluorinated Benzoate Liquid Crystals” Mol. Cryst. Liq. Cryst., 2002, 373, 1-15.

2. Yonggang Yang, Hao Chen, Geng Tang and Jianxun Wen, “Synthesis and Mesomorphic Properties of Several Series of Fluorinated Ester Liquid Crystals” Liq. Cryst., 2002, 29, 255-261.

1. Jianxun Wen, Hao Chen and Yuehai Shen, “The First Series of Ferroelectric Steroidal Fluorinated Liquid Crystals” Liq. Cryst., 1999, 26, 1833-1834.

 

 

PATENTS

4. Hao Chen and Zhixin Miao, “Method and Apparatus of Liquid Sample-Desorption Electrospray Ionization-Mass Spectrometry (LS-DESI-MS)”, U.S. Patent. 2008, In pending.

3.  Huanwen Chen, Hao Chen, Andre Venter and R. Graham Cooks, “Microspray liquid-liquid extractive ionization device”, U.S. Pat. Appl. Publ.  2008, US 2008179511.

2. Jianxun Wen, Yuehai Shen and Hao Chen, “Ferroelectric Type Fluorine-Containing Steroid Liquid Crystal, Preparation Method and Its Use” Faming Zhuanli Shenqing Gongkai Shuomingshu, 1999, 15 pp.

1. Jianxun Wen, Hao Chen and Zhigang Zhang, “Synthesis of 4-Methoxypolyfluorobenzonitriles” Faming Zhuanli Shenqing Gongkai Shuomingshu, 1998, 5 pp.