Department of Physics & Astronomy
251A Clippinger Labs
Ohio University
Athens, OH 45701
office: (740) 593-1694
lab: (740) 593-1725
fax: (740) 593-0433
E-mail: tees@ohio.edu
web: http://www.phy.ohiou.edu/~tees
Marital Status: Single
Citizenship:
Canadian (H1B1 visa)
Assistant Professor - Department of Physics and Astronomy Ohio University, Athens, OH, U.S.A. (Aug, 2001 - present )
Ph. D. (Physics), January, 1996 - McGill University, Montreal, QC, Canada
M. Sc. (Atmospheric Physics), October, 1989 - McGill University, Montreal, QC, Canada
B. Sc. (Physics), June, 1986 - McGill University, Montreal, QC, Canada
Research Associate - Chemical Engineering, University of Pennsylvania, Philadelphia, PA, U.S.A. (Oct, 2000 - Aug, 2001) Research on the biophysics of cell adhesion (supervisor: Daniel A. Hammer).
Postdoctoral Researcher - Chemical Engineering, University of Pennsylvania, Philadelphia, PA, U.S.A. (Aug, 1996 - Oct, 2000) Research on the force dependence of reverse reaction rates for selectin-carbohydrate bonds (supervisor: Daniel A. Hammer).
Postdoctoral Researcher - Chemical Engineering, Cornell University, Ithaca, NY , U.S.A. (Dec, 1995 - Aug, 1996) Research on the force dependence of reverse reaction rates for selectin-carbohydrate bonds (supervisor: Daniel A. Hammer).
Graduate Research Assistant - Ph.D. McGill University, Montreal, QC, Canada (Aug, 1989 - Nov, 1995) Thesis: On the time and force dependence of antigen-antibody mediated cell adhesion. (supervisor: Harry L. Goldsmith)
Graduate Research Assistant - M. Sc. McGill University, Montreal, QC, Canada (Aug, 1986 - Aug,1989) Thesis: Range dependence of radar estimates of rainfall: a simulation (supervisor: Geoffrey L. Austin)
1997-1999 - Recipient of two-year postdoctoral fellowship from Quebec research funding agency Fonds pour la Formation de Chercheurs et l'Aide à la Recherche (FCAR)
July, 1995 - Whitaker Foundation Travel Award from the North American Society of Biorheology for travel to 9th International Conference of Biorheology in Big Sky, Montana.
Ohio University: PHYS 201 - Introductory mechanics for non-physical science students - fall 2003. Click here to see Fluid Mechanics Supplement I prepared for the class to augment the treatment in Cutnell & Johnson.
Ohio University: PHYS 202 - Introductory mechanics for non-physical science students - spring 2003, Winter 2004, Spring 2004. Started using Personal Response System (PRS) as part of effort to do more conceptual teaching with more active learning.
Ohio University: PHYS 262 - Introductory physics with biological applications - Winter 2003
Ohio University: PHYS 469/569 - Cell & Molecular Biophysics - Fall 2002; Replaced by PHYS 461/561 - Fall 2004.
Ohio University: PHYS 299T - Tutorial in thermodynamics, electricity and magnetism for physics majors in Honors Tutorial College (2 students) - Spring 2002
Ohio University: PHYS 201 - Introductory mechanics for non-physical science students - Winter 2002
University of Pennsylvania: Instructor, CHE 410 - Chemical Engineering senior Unit Operation laboratory - Fall, 1999 & 2000
Member of Biophysical Society, Biomedical Engineering Society
American Chemical Society, American Physical Society and AAAS.Reviewer of 10 papers for Biophysical Journal and Biorheology
Tees, D.F.J. and D.J. Goetz. Leukocyte adhesion: An exquisite balance of hydrodynamic and molecular forces. News in Physiological Sciences, 18:186-190, 2003. (Abstract) (PDF)
Tees, D.F.J., K.-C. Chang, S. D. Rodgers, and D. A. Hammer. Simulation of cell adhesion to bioreactive surfaces in shear: the effect of cell size. Industrial and Engineering Chemistry Research 41:486-493, 2002. (Abstract) (PDF)
Tees, D.F.J., J.T. Woodward, and D.A. Hammer. Reliability theory for receptor-ligand bond dissociation. Journal of Chemical Physics, 114:7477-7482, May 1, 2001. (Full Text) (PDF)
Tees, D.F.J., R.E. Waugh, and D.A. Hammer. A microcantilever device to assess the effect of force on the lifetime of selectin-carbohydrate bonds. Biophysical Journal, 80:668-682, February 2001. (Abstract) (PDF)
Chang, K.-C., Tees, D.F.J., and D.A. Hammer. The state diagram for cell adhesion under flow: leukocyte rolling and firm adhesion. Proceedings of the National Academy of Sciences U.S.A., 97:11262-11267, 2000. (Abstract) (PDF) Paper received an "Editor's Choice" notice in Science, 290:235, 2000
Long, M., H.L. Goldsmith, D.F.J. Tees, and C. Zhu. Probabilistic modeling of shear-induced formation and breakage of doublets cross-linked by receptor-ligand bonds. Biophysical Journal, 76:1112-1128, 1999. (Abstract) (PDF)
Tees, D.F.J., and H.L. Goldsmith. Kinetics and locus of failure of receptor-ligand mediated adhesion between latex spheres. I. Protein-carbohydrate bond. Biophysical Journal, 71:1102-1114, 1996. (Abstract)
Kwong, D., D.F.J. Tees, and H.L. Goldsmith. Kinetics and locus of failure of receptor-ligand mediated adhesion between latex spheres. II. Protein-protein bond. Biophysical Journal, 71:1115-1122, 1996. (Abstract)
Tees, D.F.J., O. Coenen and H.L. Goldsmith. Interaction forces between red cells agglutinated by antibody. IV. Time and force dependence of break-up. Biophysical Journal 65:1318-1334, 1993. (Abstract) (PDF)
Fabry, F., G.L. Austin and D. Tees. The accuracy of rainfall estimates by radar as a function of range. Quarterly Journal of the Royal Meteorological Society, 118:435-453, 1992.
Goldsmith, H.L., S.P. Tha, and D.F.J. Tees. Red blood cell aggregation by monoclonal antibodies. In: Hémorhéologie et agrégation érythrocytaire. Applications cliniques. (J.F. Stoltz, ed.) Editions Médicales Internationales, Cachan, France, 1994. pp. 5-12.
Goldsmith, H.L., K. Takamura, S. Tha and D. Tees. Study of cell-cell interactions with the travelling microtube. In: Studying Cell Adhesion, (P. Bongrand, P. Claesson and A. Curtis, eds.) Springer Verlag, Heidelberg, New York, 1994, pp. 141-156.
01/6/24 Tees, D.F. J. Molecular Mechanics of E-selectin/Sialyl LewisX Recognition Evaluated by a Microcantilever Device, 2nd Virginia Colloquium on Biomechanics of Cell Adhesion, Charlottesville, VA.
99/11/4 Tees, D.F.J. Adhésion leucocytaire. Journées scientifiques, U. de Nancy, Nancy, France.
99/10/16 Tees D.F.J., R.E. Waugh, D.A. Hammer. Force dependence of E-selectin/sialyl-Lewisx single bond dissociation. Annual meeting of the Biomedical Engineering Society, Atlanta, GA.
98/10/12 Tees, D.F.J., R.E. Waugh, K.-C. Chang, and D.A. Hammer. Dependence of E-selectin/sialyl Lewisx reverse reaction rates on applied force. Annual meeting of the Biomedical Engineering Society, Cleveland, OH. Published in Annals of Biomed. Eng. 26:S-29, 1997.
98/8/25 Tees, D.F.J., K.-C. Chang, R.E. Waugh, and D. A. Hammer. Measurement of the force dependence of E-selectin/sialyl Lewisx reverse reaction rates using a microcantilever technique. ACS Symposium on Microscopy Techniques in Bio-Interfacial Science, Boston, MA.
98/5/2 Tees, D.F.J. and D. A. Hammer. Predicting cell adhesive behavior from the force dependence of receptor-ligand reaction rates. 3rd annual Delaware Valley Soft Materials Symposium, Philadelphia, PA.
Department of Chemical Engineering, Ohio University, Athens, OH, May, 2002
Department of Physics, University of Cincinnati, Cincinnati, OH, November, 2001
National Institute of Standards & Technology, Gaithersburg, MD, August, 2001
Department of Physics & Astronomy, Ohio University, Athens, OH, June, 2001
Department of Physics, Dalhousie University, Halifax, NS, May 2001
Department of Bioengineering, University of California San Diego, CA, April, 2001
Department of Physics, University of Alberta, Edmonton, AB, March, 2001
Department of Chemical Engineering, University of Maryland, College Park, MD, March, 2001
Department of Physics, University of Illinois at Chicago, Chicago, IL, February, 2001
Department of Chemical Engineering, University of Florida, Gainesville, FL, February, 2001
Department of Chemical Engineering, McMaster University, Hamilton, ON, February, 2001
Department of Physiology and Biophysics, SUNY Buffalo, Buffalo, NY, January, 2001
Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, June, 2000.
Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, May, 2000.
Department of Physics, University of Waterloo, Waterloo, ON, March, 2000.
Department of Chemical Engineering, University of Oklahoma, Norman, OK, February, 2000.
Department of Physics, Drexel University, Philadelphia, PA, April, 1999.
Department of Physics, Villanova University, Villanova, PA, November, 1998.
04/10/10 Sundd, P., X. Zou, D.J. Goetz, and D.F.J. Tees. Leukocyte adhesion in capillary-sized, ligand-coated micropipettes. Annual meeting of the Biomedical Engineering Society, Philadelphia, PA.
04/04/10 Tees, D.F.J., P. Sundd, X. Zou, D.J. Goetz. Leukocyte adhesion and mechanical plugging in adhesion molecule-coated micropipettes. Experimental Biology, Washington, DC.
03/10/03 Sundd, P., X. Zou, D.J. Goetz, and D.F.J. Tees. Cancer cell adhesion and mechanical plugging in adhesion molecule-coated micropipettes. Annual meeting of the Biomedical Engineering Society, Nashville, TN.
02/07/11 Tees, D.F.J., Woodward, J.T., and Hammer, D.A. The effect of multivalency on estimation of Bell model parameters for bond dissociation rates from forced unbinding assays. 3rd Virginia Colloquium on Biomechanics of Cell Adhesion, Charlottesville, VA.
02/04/10 Tees, D.F.J. and D.A. Hammer, Molecular mechanics and multivalency of E-selectin /sialyl Lewisx recognition evaluated using a microcantilever device, Keystone symposium on Molecular Mechanisms of Leukocyte Trafficking, Steamboat Springs, CO.
01/04/01 Tees, D.F.J., J.T. Woodward and D.A. Hammer. Systematic Errors in Estimation of Bell Model Parameters for Receptor-Ligand Bond Dissociation from Forced Unbinding Assays. Spring meeting of the American Chemical Society, San Diego, CA.
00/10/12 Tees, D.F.J. and D.A. Hammer. Calculation and simulation of parameter estimation for receptor-ligand bond dissociation. Annual meeting of the Biomedical Engineering Society, Seattle, WA. Published in Annals of Biomedical Engineering, 28 (supl. 1):S92.
98/11/15 Tees, D.F.J., R.E. Waugh, K.-C. Chang, and D.A. Hammer Measurement of the force dependence of E-selectin/sialyl Lewisx reverse reaction rates. Annual meeting of the American Institute of Chemical Engineers, Miami, FL.
98/4/16 Goldsmith, H.L., D.F.J. Tees, M. Long and C. Zhu. Modeling of formation and breakage of receptor-ligand bonds in shear flow. 45th annual conference of the Microcirculatory Society, San Francisco, CA. Published in FASEB J. 12:A35, 1998.
98/3/24 Tees, D.F.J., R.E. Waugh and D.A. Hammer. Measurement of the dependence of E-selectin/sialyl Lewisx reverse reaction rates on loading rate and magnitude of applied force. Keystone symposium on Molecular Mechanisms of Leukocyte Trafficking, Incline Village, NV. Abstract selected for short presentation (only 10 chosen out of ~100 abstracts).
97/10/2 Goldsmith, H.L., D.F.J. Tees, M. Long and C. Zhu. Modeling of formation and breakage of receptor-ligand bonds in shear flow. Annual meeting of the Biomedical Engineering Society, San Diego, CA. Published in Annals of Biomedical Engineering, 25:S-33, 1997.
96/08/20 Goldsmith, H.L, D.F.J. Tees and D. Kwong. Time and force dependence of the shear-induced rupture of antigen-antibody bonds. 12th International Congress on Rheology, Quebec City, QC.
96/06/16 Goldsmith, H.L., D.F.J. Tees and D. Kwong. Time and force dependence of the shear-induced rupture of receptor-ligand bonds. 70th Colloid and Surface Science Symposium, Clarkson University, Potsdam, NY.
96/04/08 Goldsmith, H.L., D.F.J. Tees and D. Kwong. Kinetics of receptor-ligand mediated adhesion of latex spheres. 43rd annual conference of the Microcirculatory Society, Washington, DC. Published in Microcirculation, 3:87, 1996.
95/07/23 Tees, D.F.J. and H. L. Goldsmith. The time and force dependence of separation of antibody agglutinated sphered red cells compared with that of blood group antigen-coupled microspheres. 9th International Congress of Biorheology/ 2nd International Congress on Clinical Hemorheology, Big Sky, MT. Published in Biorheology, 32:280, 1995.
95/04/08 Tees, D.F.J. and H. L. Goldsmith. Time and force dependence of separation of blood group B antigen-coupled microspheres cross-linked by monoclonal antibody. 42nd annual conference of the Microcirculatory Society, Atlanta, GA. Published in Microcirculation, 2:75, 1995.
93/06/14 Tees, D. and H.L. Goldsmith. Time and force dependence of separation of red cells agglutinated by monoclonal antibody. Gordon Conference on the Biorheology of Cell Adhesion, Henniker, NH. Abstract selected for short presentation (only 7 chosen out of ~30 abstracts).
93/05/26 Goldsmith, H.L. and D. Tees. Break-up of RBC aggregates: studies of the stochastic nature of receptor-ligand bonds. Conference on Recent Developments in Structured Continua III, Montreal, QC.
91/06/09 Tees, D. and H.L. Goldsmith. Stochastic nature of the interaction force between human red cells linked by monoclonal antibody. 34th annual meeting of Canadian Federation of Biological Societies, Queen's University, Kingston, ON.